| Duke at MiamiAgatha: Miami to win, 81% | 12:00 PM ET | ABC |
| Northwestern at Ohio StateAgatha: Ohio State to win, 76% | 12:00 PM ET | Fox |
| Auburn at Mississippi StateAgatha: Auburn to win, 57% | 12:00 PM ET | ESPN2 |
| Wake Forest at SMUAgatha: SMU to win, 57% | 12:00 PM ET | ESPN, Disney+ |
| Cincinnati at Iowa StateAgatha: Iowa State to win, 55% | 12:00 PM ET | TNT |
| Syracuse at NC StateAgatha: NC State to win, 71% | 12:00 PM ET | ACC Network |
| Wisconsin at MarylandAgatha: Wisconsin to win, 76% | 12:00 PM ET | FS1 |
| James Madison at UConnAgatha: James Madison to win, 82% | 12:00 PM ET | CBSSN |
| Georgia Tech at ClemsonAgatha: Clemson to win, 90% | 12:30 PM ET | CW |
| Nebraska at RutgersAgatha: Nebraska to win, 74% | 12:30 PM ET | BTN |
| Alabama at VanderbiltAgatha: Alabama to win, 88% | 12:45 PM ET | SEC Network |
| East Carolina at CharlotteAgatha: East Carolina to win, 84% | 1:00 PM ET | ESPN+ |
| UAB at TempleAgatha: UAB to win, 68% | 1:00 PM ET | ESPN+ |
| Arkansas State at Coastal CarolinaAgatha: Arkansas State to win, 57% | 1:00 PM ET | ESPN+ |
| Kansas State at TCUAgatha: TCU to win, 81% | 2:00 PM ET | ESPNU |
| Tulane at Rice | 2:00 PM ET | ESPN+ |
| Kennesaw State at Sam HoustonAgatha: Kennesaw State to win, 74% | 2:00 PM ET | ESPN+ |
| Tennessee at Texas A&MAgatha: Tennessee to win, 72% | 3:00 PM ET | ESPN |
| New Mexico State at Missouri StateAgatha: Missouri State to win, 66% | 3:00 PM ET | ESPN+ |
| Florida International at DelawareAgatha: Delaware to win, 66% | 3:00 PM ET | ESPN+ |
| Missouri at GeorgiaAgatha: Georgia to win, 87% | 3:30 PM ET | ABC, Disney+ |
| USC at IndianaAgatha: Indiana to win, 76% | 3:30 PM ET | CBS |
| Baylor at BYUAgatha: BYU to win, 75% | 3:30 PM ET | Fox |
| Michigan at OregonAgatha: Oregon to win, 88% | 3:30 PM ET | FS1 |
| Arizona State at UCFAgatha: Arizona State to win, 57% | 3:30 PM ET | ESPN2 |
| California at VirginiaAgatha: Virginia to win, 79% | 3:30 PM ET | ACC Network |
| Florida Atlantic at TulsaAgatha: Tulsa to win, 55% | 3:30 PM ET | ESPN+ |
| Nevada at Northern IllinoisAgatha: Nevada to win, 72% | 3:30 PM ET | MW+ |
| Georgia Southern at Georgia StateAgatha: Georgia Southern to win, 73% | 3:30 PM ET | ESPN+ |
| Boston College at Notre Dame | 3:30 PM ET | NBC |
| Jacksonville State at Western KentuckyAgatha: Jacksonville State to win, 82% | 3:30 PM ET | ESPN+ |
| Middle Tennessee at Liberty | 3:30 PM ET | CBSSN |
| Fresno State at Texas StateAgatha: Texas State to win, 67% | 4:00 PM ET | CW |
| Ole Miss at OklahomaAgatha: Ole Miss to win, 58% | 4:15 PM ET | SEC Network |
| Washington at Michigan StateAgatha: Washington to win, 73% | 4:15 PM ET | BTN |
| Southern Miss at Louisiana TechAgatha: Louisiana Tech to win, 94% | 5:00 PM ET | ESPN+ |
| Kansas at West VirginiaAgatha: West Virginia to win, 78% | 5:30 PM ET | ESPNU |
| App State at MarshallAgatha: Marshall to win, 71% | 6:00 PM ET | ESPN+ |
| Oregon State at Boise StateAgatha: Boise State to win, 90% | 6:00 PM ET | USA Net |
| Florida at KentuckyAgatha: Kentucky to win, 77% | 6:15 PM ET | ESPN |
| Louisville at North CarolinaAgatha: Louisville to win, 73% | 7:00 PM ET | ESPN2 |
| Minnesota at Penn StateAgatha: Penn State to win, 76% | 7:00 PM ET | FS1 |
| Troy at South AlabamaAgatha: South Alabama to win, 61% | 7:00 PM ET | ESPN+ |
| San Jose State at Air ForceAgatha: Air Force to win, 87% | 7:00 PM ET | CBSSN |
| Texas at LSUAgatha: Texas to win, 61% | 7:30 PM ET | ABC |
| Utah at ArizonaAgatha: Utah to win, 64% | 7:30 PM ET | Fox |
| Purdue at IowaAgatha: Iowa to win, 95% | 7:30 PM ET | NBC |
| Stanford at Virginia TechAgatha: Virginia Tech to win, 73% | 7:30 PM ET | ACC Network |
| UNLV at New MexicoAgatha: New Mexico to win, 82% | 7:30 PM ET | CW |
| South Carolina at ArkansasAgatha: South Carolina to win, 80% | 7:45 PM ET | SEC Network |
| North Texas at UTSAAgatha: UTSA to win, 56% | 9:00 PM ET | ESPNU |
| Texas Tech at Oklahoma State | 9:30 PM ET | ESPN |
| Utah State at San Diego StateAgatha: Utah State to win, 54% | 9:30 PM ET | USA Net |
| Wyoming at UTEPAgatha: Wyoming to win, 89% | 10:00 PM ET | FS1 |
| Colorado State at Washington StateAgatha: Washington State to win, 55% | 10:30 PM ET | CBSSN |
| North Dakota State at Hawai'iAgatha: North Dakota State to win, 80% | 11:00 PM ET | CW |