| Texas at Missouri | Texas 34, Missouri 20 | ESPN, Disney+ |
| BYU at Utah | BYU 20, Utah 28 | ABC |
| UCLA at Minnesota | UCLA 34, Minnesota 20 | Fox |
| Iowa State at Baylor | Iowa State 31, Baylor 42 | FS1 |
| Clemson at Syracuse | Clemson 18, Syracuse 13 | ESPN2 |
| Florida State at Boston College | Florida State 31, Boston College 24 | ACC Network |
| Tulsa at Tulane | Tulsa 60, Tulane 10 | ESPNU |
| North Carolina at UConn | North Carolina 38, UConn 21 | CBSSN |
| Duke at NC State | Duke 41, NC State 3 | CW |
| Maryland at Purdue | Maryland 34, Purdue 29 | BTN |
| Arkansas at Auburn | Arkansas 23, Auburn 26 | SEC Network |
| Oklahoma State at Kansas State | Oklahoma State 66, Kansas State 28 | TNT |
| Old Dominion at Coastal Carolina | Old Dominion 21, Coastal Carolina 8 | ESPN+ |
| Georgia State at App State | Georgia State 39, App State 23 | ESPN+ |
| Texas A&M at South Carolina | Texas A&M 9, South Carolina 17 | ESPN |
| UL Monroe at Arkansas State | UL Monroe 19, Arkansas State 17 | ESPN+ |
| Delaware at Kennesaw State | Delaware 40, Kennesaw State 42 | ESPN+ |
| Oregon at Ohio State | Oregon 41, Ohio State 28 | CBS |
| Alabama at LSU | Alabama 31, LSU 13 | ABC, Disney+ |
| Cincinnati at Houston | Cincinnati 24, Houston 31 | Fox |
| Merrimack at Wake Forest | Merrimack 0, Wake Forest 77 | ACC Network |
| Penn State at Washington | Penn State 28, Washington 25 | FS1 |
| Charlotte at UAB | Charlotte 12, UAB 23 | ESPN+ |
| Marshall at Georgia Southern | Marshall 13, Georgia Southern 49 | ESPN+ |
| Temple at Navy | Temple 35, Navy 42 | CBSSN |
| Western Kentucky at Middle Tennessee | Western Kentucky 42, Middle Tennessee 51 | ESPN+ |
| UCF at Kansas | UCF 33, Kansas 32 | ESPN2 |
| Rice at North Texas | Rice 23, North Texas 52 | ESPNU |
| Northern Illinois at San Jose State | Northern Illinois 19, San Jose State 30 | MW+ |
| Louisiana Tech at Troy | Louisiana Tech 41, Troy 17 | ESPN+ |
| Missouri State at Florida International | Missouri State 20, Florida International 23 | ESPN+ |
| Vanderbilt at Mississippi State | Vanderbilt 25, Mississippi State 23 | SEC Network |
| Rutgers at Wisconsin | Rutgers 10, Wisconsin 31 | BTN |
| South Alabama at Louisiana | South Alabama 26, Louisiana 28 | ESPN+ |
| Boise State at Colorado State | Boise State 64, Colorado State 38 | USA Net |
| Kentucky at Tennessee | Kentucky 6, Tennessee 34 | ESPN |
| Sam Houston at Jacksonville State | Sam Houston 14, Jacksonville State 47 | CBSSN |
| Georgia at Ole Miss | Georgia 42, Ole Miss 7 | ABC |
| Iowa at Northwestern | Iowa 24, Northwestern 10 | Fox |
| Colorado at Arizona State | Colorado 10, Arizona State 20 | ESPN2 |
| Louisville at Georgia Tech | Louisville 44, Georgia Tech 17 | ACC Network |
| Michigan State at Michigan | Michigan State 15, Michigan 6 | Peacock |
| Miami at Notre Dame | Miami 24, Notre Dame 31 | NBC |
| Air Force at Army | Air Force 24, Army 21 | CBS |
| Oklahoma at Florida | Oklahoma 23, Florida 7 | SEC Network |
| Liberty at New Mexico State | Liberty 30, New Mexico State 14 | ESPNU |
| West Virginia at Texas Tech | West Virginia 48, Texas Tech 53 | ESPN |
| Hawai'i at UTEP | Hawai'i 17, UTEP 14 | FS1 |
| Fresno State at Utah State | Fresno State 10, Utah State 17 | USA Net |
| Texas State at Oregon State | Texas State 42, Oregon State 21 | CW |
| Wyoming at UNLV | Wyoming 41, UNLV 35 | CBSSN |