| Illinois at Ohio State | Illinois 19, Ohio State 42 |
| Sam Houston at Texas Tech | Sam Houston 14, Texas Tech 49 |
| Wake Forest at Louisville | Wake Forest 30, Louisville 27 |
| Colorado at Baylor | Colorado 13, Baylor 23 |
| Virginia Tech at Boston College | Virginia Tech 21, Boston College 14 |
| San Diego State at Toledo | San Diego State 16, Toledo 41 |
| Colorado State at UTSA | Colorado State 45, UTSA 59 |
| UNLV at Akron | UNLV 38, Akron 10 |
| Ball State at Kent State | Ball State 13, Kent State 26 |
| Texas at Tennessee | Texas 20, Tennessee 17 |
| Bucknell at Pittsburgh | Bucknell 0, Pittsburgh 59 |
| South Alabama at Kentucky | South Alabama 21, Kentucky 45 |
| Lindenwood at Eastern Michigan | Lindenwood 3, Eastern Michigan 29 |
| UCLA at Maryland | UCLA 54, Maryland 3 |
| Notre Dame at Purdue | Notre Dame 49, Purdue 10 |
| Northern Illinois at Georgia State | Northern Illinois 14, Georgia State 35 |
| Central Arkansas at Florida State | Central Arkansas 7, Florida State 34 |
| Hawai'i at Wyoming | Hawai'i 10, Wyoming 27 |
| Oklahoma at Georgia | Oklahoma 13, Georgia 41 |
| Ole Miss at Florida | Ole Miss 28, Florida 52 |
| Utah at Iowa State | Utah 31, Iowa State 17 |
| Iowa at Michigan | Iowa 20, Michigan 19 |
| TCU at UCF | TCU 13, UCF 21 |
| Boise State at Western Michigan | Boise State 32, Western Michigan 7 |
| UConn at Miami (OH) | UConn 21, Miami (OH) 24 |
| William & Mary at Duke | William & Mary 7, Duke 62 |
| New Mexico at New Mexico State | New Mexico 42, New Mexico State 18 |
| Robert Morris at Buffalo | Robert Morris 28, Buffalo 31 |
| Stonehill at Ohio | Stonehill 7, Ohio 35 |
| Gardner-Webb at Marshall | Gardner-Webb 35, Marshall 36 |
| Houston at Georgia Southern | Houston 42, Georgia Southern 28 |
| North Carolina Central at East Carolina | North Carolina Central 9, East Carolina 42 |
| Vanderbilt at Auburn | Vanderbilt 15, Auburn 21 |
| Wisconsin at Penn State | Wisconsin 24, Penn State 20 |
| Nebraska at Michigan State | Nebraska 31, Michigan State 13 |
| South Florida at Bowling Green | South Florida 14, Bowling Green 6 |
| Delaware at Virginia | Delaware 3, Virginia 42 |
| James Madison at Old Dominion | James Madison 46, Old Dominion 20 |
| Incarnate Word at Texas State | Incarnate Word 10, Texas State 63 |
| Long Island University at Florida International | Long Island University 3, Florida International 20 |
| Louisiana at Charlotte | Louisiana 34, Charlotte 7 |
| Central Michigan at Miami | Central Michigan 3, Miami 52 |
| Kansas State at Cincinnati | Kansas State 26, Cincinnati 31 |
| Oklahoma State at West Virginia | Oklahoma State 41, West Virginia 24 |
| Southern Miss at Tulane | Southern Miss 21, Tulane 24 |
| Kennesaw State at Arkansas State | Kennesaw State 14, Arkansas State 17 |
| Mercyhurst at Western Kentucky | Mercyhurst 7, Western Kentucky 52 |
| Middle Tennessee at Jacksonville State | Middle Tennessee 13, Jacksonville State 23 |
| South Carolina at Alabama | South Carolina 18, Alabama 49 |
| Oregon at USC | Oregon 41, USC 27 |
| Texas A&M at LSU | Texas A&M 6, LSU 35 |
| App State at NC State | App State 31, NC State 41 |
| Arizona at Washington State | Arizona 34, Washington State 24 |
| Troy at Utah State | Troy 10, Utah State 21 |
| Houston Christian at North Texas | Houston Christian 14, North Texas 63 |
| Missouri at Mississippi State | Missouri 24, Mississippi State 31 |
| Florida Atlantic at UL Monroe | Florida Atlantic 45, UL Monroe 17 |
| Tulsa at Arkansas | Tulsa 6, Arkansas 34 |
| Missouri State at SMU | Missouri State 24, SMU 34 |
| Massachusetts at Sacramento State | Massachusetts 35, Sacramento State 6 |
| Oregon State at UTEP | Oregon State 33, UTEP 7 |
| Rice at Fresno State | Rice 24, Fresno State 38 |
| Air Force at Nevada | Air Force 36, Nevada 33 |
| Georgia Tech at Stanford | Georgia Tech 27, Stanford 34 |
| Minnesota at Washington | Minnesota 27, Washington 24 |