| Memphis at Charlotte | Memphis 59, Charlotte 8 | ESPN+ |
| Notre Dame at North Carolina | Notre Dame 37, North Carolina 26 | ESPN, Disney+ |
| Alabama at Mississippi State | Alabama 56, Mississippi State 23 | ABC |
| Boston College at SMU | Boston College 16, SMU 25 | CW |
| Michigan at Minnesota | Michigan 14, Minnesota 20 | FOX |
| UCF at Houston | UCF 17, Houston 27 | ESPN2 |
| Middle Tennessee at Kansas | Middle Tennessee 0, Kansas 55 | ESPNU |
| West Virginia at Iowa State | West Virginia 42, Iowa State 45 | TNT |
| Stanford at Wake Forest | Stanford 3, Wake Forest 57 | ACC Network |
| Syracuse at UConn | Syracuse 42, UConn 41 | CBSSN |
| Navy at Air Force | Navy 9, Air Force 14 | CBS |
| Michigan State at Wisconsin | Michigan State 3, Wisconsin 31 | BTN |
| Vanderbilt at Georgia | Vanderbilt 14, Georgia 38 | SEC Network |
| Western Michigan at Buffalo | Western Michigan 20, Buffalo 17 | ESPN+ |
| Toledo at Ball State | Toledo 39, Ball State 24 | ESPN+ |
| Ohio State at Iowa | Ohio State 31, Iowa 14 | CBS |
| Auburn at Tennessee | Auburn 14, Tennessee 24 | ESPN |
| Louisville at NC State | Louisville 28, NC State 31 | ACC Network |
| Virginia at Florida State | Virginia 7, Florida State 38 | ESPN2 |
| Akron at Central Michigan | Akron 17, Central Michigan 41 | ESPN+ |
| Eastern Michigan at Massachusetts | Eastern Michigan 38, Massachusetts 14 | ESPN+ |
| Ohio at Kent State | Ohio 13, Kent State 10 | ESPN+ |
| Bowling Green at Miami (OH) | Bowling Green 24, Miami (OH) 20 | ESPN+ |
| Old Dominion at Georgia State | Old Dominion 10, Georgia State 42 | ESPN+ |
| California at UNLV | California 31, UNLV 39 | CBSSN |
| Samford at UAB | Samford 14, UAB 33 | ESPN+ |
| Wyoming at North Dakota State | Wyoming 0, North Dakota State 28 | CW |
| Marshall at James Madison | Marshall 17, James Madison 45 | ESPNU |
| Florida at Missouri | Florida 17, Missouri 45 | ABC |
| Maryland at Nebraska | Maryland 23, Nebraska 48 | FS1 |
| UTEP at New Mexico | UTEP 7, New Mexico 61 | MW+ |
| Kentucky at South Carolina | Kentucky 35, South Carolina 34 | SEC Network |
| Purdue at Illinois | Purdue 24, Illinois 17 | BTN |
| Oregon State at Colorado State | Oregon State 56, Colorado State 26 | USA Net |
| Texas Southern at Florida Atlantic | Texas Southern 10, Florida Atlantic 66 | ESPN+ |
| Arkansas at Texas A&M | Arkansas 7, Texas A&M 34 | ESPN2 |
| BYU at TCU | BYU 17, TCU 10 | ESPN, Disney+ |
| UTSA at Rice | UTSA 16, Rice 14 | ESPN+ |
| Georgia Southern at Coastal Carolina | Georgia Southern 31, Coastal Carolina 24 | ESPN+ |
| UL Monroe at South Alabama | UL Monroe 35, South Alabama 52 | ESPN+ |
| Miami at Clemson | Miami 41, Clemson 13 | ABC |
| Washington at USC | Washington 21, USC 25 | NBC |
| Texas Tech at Colorado | Texas Tech 29, Colorado 7 | FOX |
| Temple at South Florida | Temple 17, South Florida 13 | ESPNU |
| Army at Louisiana Tech | Army 29, Louisiana Tech 31 | ESPN+ |
| Utah State at Boise State | Utah State 18, Boise State 37 | CBSSN |
| McNeese at LSU | McNeese 14, LSU 63 | SEC Network |
| Arkansas State at Louisiana | Arkansas State 20, Louisiana 23 | ESPN+ |
| Indiana at Rutgers | Indiana 47, Rutgers 15 | BTN |
| Fresno State at Washington State | Fresno State 26, Washington State 6 | USA Net |
| Baylor at Arizona State | Baylor 55, Arizona State 19 | ESPN |
| Texas State at San Diego State | Texas State 29, San Diego State 31 | CW |
| Cincinnati at Arizona | Cincinnati 7, Arizona 34 | FOX |
| San Jose State at Hawai'i | San Jose State 20, Hawai'i 16 | MW+ |