| Pittsburgh at Miami | Pittsburgh 23, Miami 52 | ESPNEWS, Disney+ |
| Indiana at Michigan | Indiana 13, Michigan 6 | Fox |
| Texas Tech at Cincinnati | Texas Tech 24, Cincinnati 37 | FS1 |
| California at SMU | California 20, SMU 59 | CW |
| West Virginia at TCU | West Virginia 24, TCU 20 | ESPN2 |
| Rutgers at Northwestern | Rutgers 14, Northwestern 42 | Peacock |
| Rice at Florida Atlantic | Rice 49, Florida Atlantic 51 | ESPNU |
| Western Michigan at Toledo | Western Michigan 38, Toledo 45 | CBSSN |
| LSU at Auburn | LSU 38, Auburn 17 | ABC |
| Baylor at Kansas | Baylor 24, Kansas 25 | TNT |
| Akron at Kent State | Akron 20, Kent State 35 | ESPN+ |
| Miami (OH) at Central Michigan | Miami (OH) 28, Central Michigan 27 | ESPN+ |
| Oregon at Illinois | Oregon 10, Illinois 21 | BTN |
| Texas A&M at Alabama | Texas A&M 20, Alabama 31 | ABC |
| BYU at UCF | BYU 31, UCF 39 | Fox |
| Iowa at Minnesota | Iowa 10, Minnesota 13 | FS1 |
| Oklahoma at Mississippi State | Oklahoma 23, Mississippi State 15 | SEC Network |
| Tennessee at South Carolina | Tennessee 24, South Carolina 27 | ESPN, Disney+ |
| Michigan State at UCLA | Michigan State 10, UCLA 28 | CBS |
| Boston College at Georgia Tech | Boston College 49, Georgia Tech 27 | ACC Network |
| Hawai'i at Northern Illinois | Hawai'i 56, Northern Illinois 21 | MW+ |
| Sacramento State at Ball State | Sacramento State 17, Ball State 34 | ESPN+ |
| Bowling Green at Buffalo | Bowling Green 24, Buffalo 31 | ESPN+ |
| North Texas at Navy | North Texas 49, Navy 39 | CBSSN |
| Kansas State at Arizona State | Kansas State 17, Arizona State 28 | ESPN2 |
| Eastern Michigan at Ohio | Eastern Michigan 20, Ohio 24 | ESPNU |
| UL Monroe at Troy | UL Monroe 21, Troy 14 | ESPN+ |
| Louisiana at Southern Miss | Louisiana 31, Southern Miss 35 | ESPN+ |
| Old Dominion at Louisiana Tech | Old Dominion 0, Louisiana Tech 26 | ESPN+ |
| San Jose State at Nevada | San Jose State 13, Nevada 28 | MW+ |
| Boise State at Washington State | Boise State 31, Washington State 10 | USA Net |
| San Diego State at Colorado State | San Diego State 49, Colorado State 56 | CW |
| Colorado at Oklahoma State | Colorado 24, Oklahoma State 57 | FS1 |
| Virginia Tech at Clemson | Virginia Tech 20, Clemson 16 | ESPN |
| Georgia State at Arkansas State | Georgia State 32, Arkansas State 38 | ESPN+ |
| Ole Miss at Texas | Ole Miss 27, Texas 34 | ABC |
| USC at Wisconsin | USC 7, Wisconsin 24 | NBC |
| Vanderbilt at Kentucky | Vanderbilt 17, Kentucky 34 | SEC Network |
| Iowa State at Arizona | Iowa State 3, Arizona 39 | ESPN2 |
| Syracuse at North Carolina | Syracuse 31, North Carolina 30 | ACC Network |
| Utah State at Texas State | Utah State 17, Texas State 20 | CBSSN |
| UTSA at Tulane | UTSA 42, Tulane 19 | ESPNU |
| Houston at Utah | Houston 13, Utah 21 | ESPN |
| North Dakota State at New Mexico | North Dakota State 16, New Mexico 21 | CW |