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Dolphins vs Bills Odds

Sunday, Nov 22, 2026, 1:00 PM ET, Highmark Stadium, Orchard Park, Week 11

Agatha Research Desk

TV: CBS

Agatha is watching this one

Agatha has no pick on this game.

Agatha prices NFL games from eight days before the start, so her call on this game can post from Sat, Nov 14 (ET).

Market (latest pregame line)

Spread (BUF)

-16.5

Total

46.5

Moneyline

MIA
+980
BUF
-1800

Line movement, tracked by Agatha since first sighting (2 snapshots)

  • Moneyline (BUF) at FanDuel: opened -1400, now -1800
  • Spread (BUF) at FanDuel: opened -16.5, now -16.5
  • Total at FanDuel: opened 46.5, now 46.5

Dolphins vs Bills injury report

Miami Dolphins

Buffalo Bills

Dolphins vs Bills recent form

Dolphins: last 5 games

Last 5: 1-4

  1. Nov 8vs Detroit LionsL9-19
  2. Nov 1vs New England PatriotsL19-24
  3. Oct 25at New York JetsW28-25
  4. Oct 11vs Cincinnati BengalsL24-31
  5. Oct 4at Minnesota VikingsL10-15

Bills: last 5 games

Last 5: 4-1

  1. Nov 9at Minnesota VikingsW23-6
  2. Nov 1vs Baltimore RavensW36-10
  3. Oct 18at Las Vegas RaidersW33-30
  4. Oct 12at Los Angeles RamsW37-34
  5. Oct 4vs New England PatriotsL26-29

Dolphins vs Bills head-to-head

Since Jan 7, 2024: Bills 4, Dolphins 1

  1. Nov 9, 2025Dolphins 30-13
  2. Sep 18, 2025Bills 31-21
  3. Nov 3, 2024Bills 30-27
  4. Sep 12, 2024Bills 31-10
  5. Jan 7, 2024Bills 21-14

Dolphins vs Bills key players

Miami Dolphins

Buffalo Bills